The prosocial domain involves stress arising through our awareness of and concern for other people. Empathy, moral concern, witnessing suffering or injustice, dealing with others’ strong emotions, and feeling responsible for someone else’s well-being can all activate a stress response and consume energy. These stresses arise from capacities we deeply value, which can make their energy cost easy to overlook. The Self-Reg shift is to recognize that caring itself can be stressful. Understanding prosocial stress helps us see that empathy and conscience do not exist outside the stress system. Supporting someone who cares deeply may sometimes mean helping them recover from the very real stress that caring can create.